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The role of clinical decision support in pharmacist response to drug-interaction alerts

Background

With over 100,000 different types of drug-drug interactions health care professionals rely heavily on automated drug-interaction alerts. Substantial variance in drug-interaction alerts yields opportunities for the use of clinical decision support (CDS) as a potential benefit to pharmacists.

Objective

The purpose of this research was to determine whether decision support during dispensing impacts pharmacist response to drug-interaction alerts.

Methods

A brief survey was administered to pharmacists in the community consisting of three patient cases, each containing three drug-drug interactions of varying severity. For each interaction, pharmacists were asked how they would respond, one group of pharmacists was randomly assigned to receive CDS while the other group did not.

Results

There were no significant differences in pharmacist response to alerts between the two groups. The control group did appear to be more likely to consult a drug reference, but this difference was not significant. While this study did not demonstrate a significant difference, drug-interaction alerts are still an area where improvements could be made. Advancements have the potential to reduce risk to patients and limit unnecessary hospital admissions.

Conclusion

This study suggests that this level of clinical decision support has limited impact, but may prove beneficial by reducing the need to consult additional references.

Authors L Miller, K Steinmetz Pater, S Corman
Journal Research in Social and Administrative Pharmacy
Therapeutic Area Other
Center of Excellence Real-world Evidence & Data Analytics
Year 2015
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