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Current management of atrial fibrillation: an observational study in NHS primary care

Objective 

To describe National Health Service (NHS) resource use and pharmacological management of atrial fibrillation (AF) in routine UK primary care.

Design 

Multicentre retrospective study.

Setting 

Seven primary care practices in England, one in Wales.

Patients 

Patients with AF were identified and approached for consent. Data were collected on the first 12 weeks post-diagnosis (‘initiation’) and, for established patients, up to the most recent 3 years of management (‘maintenance’).

Results 

Data collected on 825 patients with AF, 56% men. Mean age (at diagnosis) 70.5 years. Mean 2.4 (SD 2.2) visits to primary care per patient during the initiation phase; 1.5 (SD 1.8) per patient-year during the maintenance phase. Mean 0.4 (SD 0.6) inpatient admissions for AF per patient during the initiation phase and 0.1 (SD 0.3) per patient-year during the maintenance phase. The mean length of hospital stay per admitted patient was 5.6 days during initiation and 6.4 days per patient-year during maintenance. During the initiation phase, 46.1% (143/310) patients received a β-blocker and 97 (31.3%) received no rate/rhythm control. Only 234 (75.5%) patients received thromboprophylaxis in the 12 weeks postdiagnosis and 674 (87.7%) in the maintenance phase. 440 (57.2%) patients were deemed to be at high risk of stroke at the end of the maintenance phase; 55% (242/440) of these were receiving appropriate anticoagulation therapy.

Conclusions 

The results suggest that there are opportunities for optimisation of treatment and there is significant NHS resource associated with AF management, the details of which are invaluable for future healthcare planning and policy development in this area.

Authors G Kassianos, C Arden, S Hogan, R Dew, A Fuat
Journal BMJ Open
Therapeutic Area Cardiology
Center of Excellence Real-world Evidence & Data Analytics
Year 2013
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