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Treatment patterns and economic burden among cervical and endometrial cancer patients newly initiating systemic therapy
Aim
To evaluate treatment patterns, healthcare resource use (HCRU) and all-cause healthcare costs among patients with cervical or endometrial cancer newly initiating systemic therapy.
Methods
We identified patients with cervical or endometrial cancer newly initiating systemic therapy – a claims-based proxy for advanced disease – between 2014 and 2019, described them by line of therapy (LOT), and summarized the per patient per month (PPPM) HCRU and healthcare costs per LOT.
Results
Among 1229 patients with cervical cancer and 2659 patients with endometrial cancer, LOT1 therapies included systemic only (cervical, 50.1%; endometrial, 83.2%) and systemic with radiation therapy (cervical, 49.9%; endometrial, 16.8%). Mean PPPM total costs were: LOT1 (cervical, US$15,892; endometrial, US$11,363), LOT2 (US$20,193; US$14,019) and LOT3+ (US$16,576; US$14,645).
Conclusions
Overall, patients received guideline-concordant care and experienced significant economic burden, which increased with LOT.
Authors
N Kebede, R Shah, A Shah, S Corman, C Nwankwo
Journal
Future oncology (London, England)
Therapeutic Area
Oncology
Center of Excellence
Real-world Evidence & Data Analytics
Year
2022
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