Oncology Archives - Open Health

Patient-reported outcomes in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia receiving standard chemotherapy plus quizartinib or placebo (QuANTUM-First): a global, randomised, placebo-controlled, phase 3 trial

Authors: E N Olíva, F Cottone, S Unni, A Correges, J B Hansen, X L Marston, J Cortes, M A Sekeres Published: The Lancet Haematology, 2026 View publication Background QuANTUM-First is a...

Cost-efficiency and expanded access modeling of conversion to biosimilar bevacizumab in metastatic colorectal and non-squamous non-small cell lung cancer in Medicare

Authors: J A Roth, D Kratochvil, S Dorman, M Bernauer Published: Journal of Medical Economics, 2025 View publication Background Biosimilars to originator bevacizumab (Avastin), such as bevacizumab-bvzr (Zirabev), can deliver substantial savings...

Indirect Comparison of Epcoritamab Versus Axicabtagene Ciloleucel in Chimeric Antigen Receptor T-Cell-Eligible and -Naive Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Authors: G Salles, C P Fox, M Hamadani, A Wang, K Sail, A Alshreef, M Moran, A Mutebi, J Blaedel, V Chirikov, C Thieblemont Published: Clinical Lymphoma, Myeloma and Leukemia, 2025 View...

Postimmunotherapy and vascular endothelial growth factor inhibitor landscape in advanced renal cell carcinoma: Treatment patterns, costs, and outcomes

Authors: N J Shah, R Shinde, R Bhattacharya, T LeMasters, N Ning, J Schmier, M Tan, D Vickery, R Perini, R J Motzer Published: JCO Oncology Practice, 2025 View publication Purpose With...

Venetoclax in combination with obinutuzumab in previously untreated fit patients with chronic lymphocytic leukemia: A Canadian cost-utility analysis

Authors: G van de Wetering, C Owen, V Banerji, A Gosselin, S Kamdar, N P Roc, L Bakker, G Ratnaparkhi, S Barakat, C Vicente, B S Manzoor Published: PharmacoEconomics – Open, 2025...

Cardiovascular safety outcomes of chronic lymphocytic leukemia treatments: A systematic and targeted literature review

Authors: Y-C Chen, P Miranda, Y K Barqawi, G E Fox, C Chukwu, J Moslehi, R P O'Quinn Published: Critical Reviews in Oncology/Hematology, 2025 View publication Abstract Chronic lymphocytic leukemia (CLL) treatments,...

Type of pre-existing chronic conditions and their associations with Merkel cell carcinoma (MCC) treatment: Prediction and interpretation using machine learning methods

Authors: Y P V Mbous, Z A Siddiqui, M Bharmal, T LeMasters, J Kolodney, G A Kelley, K Kamal, U Sambamoorthi Published: PLOS ONE, 2025 View publication Objective This study examined the...

Q-TWiST analysis of first-line nivolumab plus chemotherapy versus chemotherapy in patients with advanced gastric cancer, gastroesophageal junction cancer, or esophageal adenocarcinoma from CheckMate 649: 4-year follow-up results

Authors: D Lin, W Quan, M Garretson, V Chirikov, C Chen, P Singh, C Davis, R Sugarman Published: Gastric Cancer: Official Journal of the International Gastric Cancer Association and the Japanese Gastric...

Enfortumab vedotin plus pembrolizumab versus chemotherapy in patients with previously untreated locally advanced or metastatic urothelial cancer (EV-302): patient-reported outcomes from an open-label, randomised, controlled, phase 3 study

Authors: S Gupta, Y Loriot, M S Van der Heijden, J Bedke, B P Valderrama, E Kikuchi, A Fléchon, D Petrylak, M De Santis, M D Galsky, J L Lee 11, U...

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