Written by Charlotte Johnston on Friday 15th February 2019
Antimicrobial resistance (AMR) has become an issue globally, inhibiting our ability to effectively treat a number of microbial infections. With an estimated 700,000 people globally estimated to die annually due to the effects AMR and no novel classes of antibiotics discovered since the 1980s, it is not surprising that measures are being put in place to tackle this problem at both a global and national level. Around 50% of drugs used today were discovered during the golden age of antibiotic discovery, 1950-1960, with commonly used drugs such as penicillin and streptomycin discovered over 80 years ago and 70 years ago respectively.
The newly published governmental five year AMR strategy builds on prior work achieved through the five year AMR strategy from 2013-2018. The latest article describes their new action plan, ultimately developed in order to accomplish the 20 year vision for AMR which aims to see the following:
The strategy has outlined that it aims to support the global AMR movement within the UK through facilitating the development of novel diagnostics, therapies and vaccines, aiming to create a full R&D pipeline for these products.
Following the release of the five year AMR strategy on the 24th January, OPEN VIE (formerly pH Associates, Harvey Walsh and Open Access Consulting) have been considering the positive impact that this governmental plan may have on our pharmaceutical clients and also on ourselves as a consultancy.
What does this mean for our clients?
The production of novel therapeutics as well as diagnostic tools is currently heavily incentivised by the government along with initiatives to improve wider understanding around AMR:
Governmental incentives in this area are enabling pharmaceutical companies to explore areas they previously had not considered, and give the opportunity for the pharmaceutical industry to lead the way in changing the antimicrobial market.
There is also an opportunity here for pharmaceutical companies to be innovative through the design, development and implementation of novel diagnostic tools in the antimicrobial space. This five year AMR strategy intends to make these diagnostic tools more easily accessible to clinicians and their patients through access schemes funded by the government.
What does this mean for us as a consultancy and how can we support our clients?
The government has placed a strong emphasis on enhancing existing datasets to improve the understanding of resistance and therefore inform future therapies and diagnostics. This provides an opportunity for OPEN VIE to support our clients through exploring these existing datasets:
Within the real world evidence group, OPEN VIE has nineteen publications focussing on infectious disease and a further two publications in development focussing on resistant bacterial infections and their burden upon healthcare resource use. Please find a selection of our published work below:
Impact of recurrent Clostridium difficile infection: Hospitalisation and patient quality of life
Read the full publication
The burden of healthcare resource utilisation in patients with complicated acute bacterial skin and skin structure infections (ABSSSI) where first line beta-lactam antibiotics were unsuitable
Read the full publication
Economic evaluation of treatment for MRSA complicated skin and soft tissue infections in Glasgow hospitals.
Read the full publication
A variety of methodologies have been implemented in these studies including local service evaluations, retrospective chart reviews and prospective research studies.
Working in partnership with our clients, we embrace our different perspectives and strengths to deliver fresh thinking and solutions that make a difference.
Together we can unlock possibilities.
For information about OPEN Health’s services and how we could support you, please get in touch.